Grey's Histology Report

                                                             
Here is Grey's histology report. The difficulty we have in comparing them to other MCTs is that most of the comparable data is for dermal MCTs. Grey's was subcutaneous within the tissue.  

I've been invited to join a weim group on Facebook where there is more experience of dealing with MCTs. So far have only heard of Grey as the Slovak with this condition.

He's on fine form. Being very well behaved at home without being offlead for over a week.                                                                   
                                             
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      ASG  : 4.7mth m SlovRHairPoint    
      Report Date  : 04/12/12  
      Request Date  : 30/11/12  


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Histology
Diagnosis        Mast Cell Tumour
Prognosis        Fair but possible recurrence, requiring attention.

Mass caudal right shoulder -
Breed: Slovakian Rough Haired Pointer (SRHP)

1 sample received; 3 sections examined
Adipose tissue: Expanding the subcutaneous fat tissue is a
neoplasm composed of loosely arranged sheets and cords of
neoplastic mast cells. Neoplastic cells are round, with distinct
cell borders and moderate amounts of pale amphophilic
cytoplasm with fine granulation. Nuclei are round and centrally
located, with finely stippled chromatin and small or
inconspicuous nucleoli. Mitoses are rarely observed, averaging
less than 1 per 10/400x fields, and there is minimal cellular
atypia. Larger numbers of eosinophils are scattered throughout
the neoplasm. The center of the sample is cystic. The neoplasm
appears to have been completely excised in the section
examined.

COMMENT:
This is a subcutaneous mast cell tumour. A recent study
suggests that most subcutaneous mast cell tumours are cured
surgically with a low incidence of recurrence and lymph node
metastasis. There is a more favourable prognosis for mast cell
tumours such as this that have a low mitotic index with only
minor invasive growth. Please note that the grading schemes
used for dermal mast cell tumours have not been validated for
subcutaneous mast cell tumours like the one present here.
However, if this mast cell tumour was present in the dermis,
then it would be compatible with an intermediate grade (Grade
II) neoplasm.