Can you help? 6 year old Eva (Aucassin Despina) very sick with suspected AI Disease

Sadly the new year didn't get off to a good start for this 6 year old female Slovak called Eva (Aucassin Despina, d.o.b. 17/12/2005). I was contacted by her owner who is desperately looking to bring her back to health. She's been struck down with what looks like another of those mysterious Auto Immune Disease (AI) conditions, and has lost the use of her hind legs with suspected hind limb ataxia. She comes from what sounds like an awfully sick litter of Slovaks with a few of her siblings having died at young ages. Her brother had hind limb ataxia at 18 months of age (he later died). Eva herself has had a life of overcoming sickness, since 16 weeks old she suffered with AI issues and meningitis problem. Her pedigree is the same mating that was repeated two years later and produced one of the main stud dogs in the UK, Bruce (Aucassin Tonto of Rosetinted). They both therefore share the COI of 20.3%. You can see from the pedigree their breeding, hence the high COI. The inbreeding coefficient of Slovakian Rough Haired Pointers is 11.5%.

Eva's parents are Sholto de ''Etang aux Colverts x Aucassin Comfrey.

The problem I've seen with so many of these mysterious AI pain issues that have come to light that result in steroid or anti-biotic treatment, there seem to be as many diagnoses as there are dogs. But one thing they all share is how distressing it is for the dogs and their owners. So if you think you can help with advice or experience, or if your Slovak is related to Eva, please get in touch: greytheslovak@gmail.com and I'll forward it on.

If you suspect your own Slovak might have had a health concern, no matter how minor, that you can now recall, please do take the time to fill out a health report for the breed club. Did you have a pup that reacted badly to vaccinations? Any pain incidents that seemed strange? It is only through reporting of issues within our breed that we can help get to the bottom of conditions like this. The link to the health form is on the breed club website to download.

Here is the lovely Eva (aka giant Doof) in happier days spaniel sitting this summer.

Eva has now had a max dexamethasone jab, after which she picked up so it does look to be auto-immune related rather than trauma.

She is now on prednisolone at 4x original dose ie maximum plus antibiotics in case there is a spinal infection. Problem looks to be at L4/5 or thereabouts.

When Eva was small she had recurrent bouts of elevated temperature, pain, neck stiffness, loss of appetite all responsive to steroids from around 16 weeks on. The attacks put her on a drip in the surgery if not spotted quickly enough. Then decreasing attacks and almost no problems for 2 years with the last 12 months clear. One week ago she was looking for pheasants in fields. She had slightly stiff neck next day, no temperature, but over 3 days reducing hind limb proprioception ending up in loss of motor power and no response to pain. Very sudden and a new manifestation.

Her brother died in England at around 2 years after a lifetime of the symptoms suffered by Eva although he had some loss of proprioception earlier. Another sibling died at a few months of age in the breeder's vets. Another sibling was ill.

Really hoping that Eva recovers soon. If you think you can help, please do get in touch.